@ncoonce Your sound should be working. What version of AGS are you currently running?
Unfortunately, the directional controls on some N64 games need to be remapped to work with the joystick (The original N64 controller had a DPad and a Joystick whereas the Polycade only has 1 joystick )
We have instructions on this in the Console ROM section here:
#55
Someone else on this thread had a similar issue as well:
#40 . Perhaps their instructions will assist you better than the ones we wrote in the first post I linked to.